Is burnout inevitable during medical training?

Medical training in the United States is a long and tedious process. It begins in college, when one must complete the mandatory prerequisite curriculum and take a medical entrance exam; your score on which is directly compared to other applicants, immediately labeling you as a competitive candidate or not. The process of applying requires the […]

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma

Durable responses in metastatic cancers have been achieved with a variety of immunotherapies such as interleukin-2, adoptive cell transfer of tumor-infiltrating lymphocytes, antibodies that block cytotoxic T-lymphocyte–associated antigen 4 (CTLA4),1-5 and antibodies that block programmed death 1 (PD-1).6-10 However, in a recent study, approximately 25% of patients with melanoma who had had an objective response […]

Cervical Carcinoma

Worldwide, cervical carcinoma is the second most common female malignancy, causing approximately 500,000 new cases each year.1 It is responsible for 274,000 deaths and is the third most common cause of female mortality. In Europe the crude mortality rate is 5.9/100,000 women/year but the mortality rate is 10 times higher in developing countries. It has […]

Role of glucocorticoids in the physiopathology of excessive fat deposition and insulin resistance.

  Glucocorticoids are important hormones in the regulation of metabolic homeostasis. We infused normal ratswith dexamethasone given intracerebroventricularly (i.c.v.) for 3 days. This resulted in hyperphagia,hyperinsulinemia, and marked insulin resistance. Similar metabolic defects were observed following i.c.v. infusion of neuropeptide Y (NPY) in normal rats. As central dexamethasone infusion enhanced NPY content in the arcuate […]

Top 10 Tips for New Medical Students

In a few weeks’ time, our medical school will welcome into its fold a new batch of medical students. I know they’re excited. I also know that right now they are completely in the dark. They think they know what they got themselves into, but most of them don’t. I know that, because I’ve been […]

What is a Medical Scribe?

A Medical Scribe is a revolutionary concept in modern medicine.  Traditionally, a physician’s job has been focusing solely on direct patient contact and care.  However, the advent of the Electronic Health Record (EHR) created an overload of documentation and clerical responsibilities that slows physicians down and pulls them away from actual patient care. To relieve […]

What kind of doctor do you want to be? Think about it.

“A doctor’s mission should not be just to prevent death, but to improve the quality of life. You treat a disease, you win-you lose. You treat a person, I guarantee you’ll win, no matter what the outcome.” – Patch Adams (1998) It’s that time of year where everyone begins residency applications, and you commonly hear […]

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